The project aims to take advantage of the near-infrared (NIR) emission of lanthanide ions (LnIII) in an innovative multiplex imaging approach to establish an accurate map of SKCa channel subtypes and to correlate it with a disease prognosis and/or to optimize treatments. To achieve this goal, a series of imaging probes based on lanthanide(III)/gallium(III) metallacrowns exhibiting fingerprint bright emission in the NIR range and conjugated to peptides with controlled specificity for the SKCa family will be prepared.

The seventh FrenchBIC online webinar will take place on October Wednesday 19th at 10.30am, and it will be given by: Svetlana Eliseeva (CBM, Orléans), Lanthanide(III)/gallium(III) and lanthanide(III)/zinc(II) metallacrowns for near-infrared luminescence and photoacoustic imaging (abstract); Benoît Bertrand (Sorbonne Université), Biphenyl-gold(III) scaffold: a new field of investigations for anticancer drug candidates (abstract). The format of the seminar is two 30+10 min talks, followed by a meeting time in an online space for informal discussions. The seminar will be given online, there: …

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